What happened since then?
Since then, a remarkable 139 papers authored by 370 researchers from 123 institutions in the US and Europe have furthered the field. Our compilation, containing peer-reviewed articles and abstracts, strives to be a comprehensive resource in migraine treatment research.
While exploring, consider search terms like neurostimulation, occipital nerve stimulation, neuromodulation, cluster headache treatment, occipital neuralgia treatment, migraine research, and more.
Our curated collection includes 111+ clinical reports and 28 abstracts, available for download by clicking on the titles. Your contributions to this resource are appreciated – should you know of any missing articles, please get in touch.
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Abhinav K, Park ND, Prakash SK, Love-Jones S, Patel NK. Novel Use of Narrow Paddle Electrodes for Occipital Nerve Stimulation—Technical Note.
Neuromodulation: Technology at the Neural Interface 2013;16:607-609.
Arcioni R, Martelletti P. Refractory chronic migraine: Therapy with combined peripheral neurostimulation. In: Siva A, Lampl C, eds. Case-Based Diagnosis and Management of Headache Disorders.
Switzerland: Springer International Publishing, 2015: 75-80.
Bermejo PE, del Pozo C, Parodi E, Ahijado J, Rey P. EHMTI-0224. Occipital nerve stimulation for drug-resistant chronic migraine: increasing experience.
The Journal of Headache and Pain 2014;15:1-1.
Bulger R, Conidi F, Reed KL. Combined supraorbital (SONS) and occipital nerve stimulation (ONS) for intractable post-herpetic neuralgia (P7.317).
American Academy of Neurology 2014 Annual Meeting; 2014; Philadelphia, PA: American Academy of Neurology: P7.317.
Carayannopoulos AG. Teaching case: occipital neuralgia in a young patient.
Headache 2007;47:1367-1370.
Clark SW, Wu C, Boorman DW, et al. Long‐Term Pain Reduction Does Not Imply Improved Functional Outcome in Patients Treated With Combined Supraorbital and Occipital Nerve Stimulation for Chronic Migraine.
Neuromodulation: Technology at the Neural Interface 2016.
Clarke C, Azari P, Huh B. Damaged insulation mimicked symptoms of occipital stimulator lead migration.
Neuromodulation 2011;14:539-540; discussion 541.
Datta S, Reed KL, Will KR. Combined supraorbital (SONS) and occipital nerve stimulation (ONS) in failed surgical treatment of migraine: case report and review of the literature [abstract].
American Society of Intervention Pain Physicians 2012 Annual Meeting; 2012; Washington DC: Pain Physician: E541-572.
Dodick DW. Occipital nerve stimulation for chronic cluster headache.
Advanced Studies in Medicine 2003;3:S569-S571.
Dunteman E. Peripheral nerve stimulation for unremitting opthalmic posherpetic neuralgia.
Neuromodulation 2002;5:279-290.
Elahi F, Reddy C. Neuromodulation of the great auricular nerve for persistent post-traumatic headache.
Pain Physician 2014;17:E531-536.
Elahi F, Reddy C, Bellinger A, Manolitsis N. Neuromodulation of the great auricular aerve: a case report.
Neuromodulation 2014;17:784-787.
Eldrige JS, Obray JB, Pingree MJ, Hoelzer BC. Occipital neuromodulation: ultrasound guidance for peripheral nerve stimulator implantation.
Pain practice : the official journal of World Institute of Pain 2010;10:580-585.
Ellis J, Gill B, Pisapia D, Winfree C. Superficial temporal artery pseudoaneurysm following trigeminal nerve stimulator placement.
Neuromodulation 2014;17:788-790.
Ellis J, Mejia Munne J, Winfree C. Trigeminal branch stimulation for the treatment of intractable craniofacial pain.
J Neurosurg 2015;123:283-288.
Falowski S, Wang D, Sabesan A, Sharan A. Occipital nerve stimulator systems: review of complications and surgical techniques.
Neuromodulation: Technology at the Neural Interface 2010;13:121-125.
Fontaine D, Sol JC, Raoul S, et al. Treatment of refractory chronic cluster headache by chronic occipital nerve stimulation.
Cephalalgia 2011;31:1101-1105.
Franzini A, Messina G, Leone M, Broggi G. Occipital nerve stimulation (ONS). Surgical technique and prevention of late electrode migration.
Acta Neurochir (Wien) 2009;151:861-865; discussion 865.
Ghaemi K, Capelle HH, Kinfe TM, Krauss JK. Occipital nerve stimulation for refractory occipital pain after occipitocervical fusion: expanding indications.
Stereotact Funct Neurosurg 2008;86:391-393.
Hammer M, Doleys D. Perineuronal stimulation in the treatment of occipital neuralgia: a case study.
Neuromodulation 2001;4:47-51.
Hann S, Sharan A. Dual occipital and supraorbital nerve stimulation for chronic migraine: a single-center experience, review of literature, and surgical considerations.
experience, review of literature, and surgical considerations.
Hayek SM, Jasper JF, Deer T, Narouze S. Occipital neurostimulation-induced muscle spasms: implications for lead placement.
Pain Physician 2009;12:867-876.
Johnstone CS, Sundaraj R. Occipital nerve stimulation for the treatment of occipital neuralgia-eight case studies.
Neuromodulation 2006;9:41-47.
Jones RL. Occipital nerve stimulation using a medtronic resume II electrode array.
Pain Physician 2003;6:507-508.
Kiss ZH, Becker WJ. Occipital stimulation for chronic migraine: Patient selection and complications.
The Canadian Journal of Neurological Sciences 2012;39:807-812.
Kovacs S, Peeters R, De Ridder D, Plazier M, Menovsky T, Sunaert S. Central effects of occipital nerve electrical stimulation studied by functional magnetic resonance imaging.
Neuromodulation 2011;14:46-55; discussion 56-47.
Lambru G, Shanahan P. Occipital nerve stimulation in the treatment of medically intractable SUNCT and SUNA.
Pain physician 2014;17:29-41.
Li D, Xiao L. Combining botulinum toxin (a) injection with peripheral nerve stimulation in a patient for intractable ophthalmic postherpetic neuralgia.
Neuromodulation: Technology at the Neural Interface 2015.
Magis D, Gérard P, Schoenen J. Invasive occipital nerve stimulation for refractory chronic cluster headache: what evolution at long-term? Strengths and weaknesses of the method.
The Journal of Headache and Pain 2016;17:1-5.
Mammis A, Gudesblatt M, Mogilner AY. Peripheral neurostimulation for the treatment of refractory cluster headache, long-term follow-up: case report.
Neuromodulation 2011;14:432-435; discussion 435.
Miller S, Watkins L, Matharu M. Long-term outcomes of occipital nerve stimulation for chronic migraine: a cohort of 53 patients.
The Journal of Headache and Pain 2016;17:1-15.
Picaza JA, Hunter SE, Cannon BW. Pain suppression by peripheral nerve stimulation.
Appl Neurophysiol 1977;40:223-234.
Pingree MJ, Eldrige JS. Occipital Neuromodulation: A Surgical Technique with Reduced Complications.
Pain Physician 2016;19:E1005-E1012.
Ramineni T, Prusik J, De La Cruz P, et al. The Impact of Peripheral Nerve Stimulation on Disability and Depression
Neuromodulation: Technology at the Neural Interface 2015:n/a-n/a.
Reed KL, Linder S, Will KR, Bulger R. Combined occipital and supraoribital neurostimulation for chronic migraine headaches in adolescents (Ages 14-19); a retrospective analysis of 23 consecutive patients [abstract].
2013 Congress of the International Headache Society. Boston, MA: Cephalalgia, 2013: 198-199.
Reed KL, Will KR, Bulger R, Dattta S, Rupert M, Linder S. Combined occipital and supraorbital neurostimulation for chronic migraine headachess: a multicenter retrospective analysis of 171 consecutive patients [abstract].
2013 Contgress of the International Headache Society. Boston, MA: Cephalalgia, 2013: 197-198.
Reed KL, Will KR, Chapman J, Richter E. Combined occipital and supraorbital neurostimulation for chronic migraine headaches: an extended case series [abst].
15th Congress of the International Headache Society. Berlin, Germany: Cephalalgia, 2011: 98-99
Reverberi C, Bonezzi C, Demartini L. Peripheral Subcutaneous Neurostimulation in the Management of Neuropathic Pain: Five Case Reports.
Neuromodulation: Technology at the Neural Interface 2009;12:146-155.
Royster EI, Crumbley K. Initial Experience With Implanted Peripheral Nerve Stimulation for the Treatment of Refractory Cephalgia.
The Ochsner Journal 2011;11:147-150.
Seixas T, Liça L, Ribeiro B, Batista A, Cortez J, Silva DJ. Chronic cluster headache treated with occipital and supraciliary nerve stimulation‐a new approach: 14AP2‐10.
European Journal of Anaesthesiology (EJA) 2013;30:210-210.
Serra G, Marchioretto F. Occipital nerve stimulation for chronic migraine: a randomized trial.
Pain Physician 2012;15:245-253.
Sharan A, Narouze S, Trentman TL, et al. Peripheral nerve stimulation of the occipital nerves for the management of headache pain and disability associated with chronic migraine: technical considerations from a prospective, multicenter, double-blinded, controlled study.
North American Neurostimulation Society Annual Meeting; 2011; Las Vegas, Nevada.
Shin JH, Kim YC, Jang IK, Kim JH, Park SY, Lee SC. Occipital nerve stimulation in a patient with an intractable chronic headache -A case report.
Korean J Anesthesiol 2011;60:298-301.
Silberstein SD, Dodick D, Saper JR, et al. The safety and efficacy of peripheral nerve stimulation for the management of chronic migraine.
North American Neurostimulation Society Annual Meeting. Las Vegas, Nevada2011.
Silberstein SD, Dodick D, Saper JR, et al. Efficacy of occipital nerve stimulation for the management of intractable, chronic migraine: results from a prospective, multicenter, double-blinded, controlled study.
2012 American Headache Society 54th Annual Scientific Meeting. Los Angeles, Ca2012: 866.
Slavin KV. Occipital nerve stimulation for treatment of severe occipital headaches (p abs).
Cephalalgia 2003;23:755.
Slavin KV, Nersesyan H, Wess C. Peripheral neurostimulation for treatment of intractable occipital neuralgia.
Neurosurgery 2006;58:112-119; discussion 112-119.
Slavin KV, Vannemreddy PS. Repositioning of supraorbital nerve stimulation electrode using retrograde needle insertion: a technical note.
Neuromodulation 2011;14:160-163; discussion 163-164.
Slavin KV, Wess C. Trigeminal branch stimulation for intractable neuropathic pain: technical note.
Neuromodulation 2005;8:7-13.
Stidd DA, Wuollet A, Bowden K, et al. Peripheral nerve stimulation for trigeminal neuropathic pain.
Pain Physician 2012;15:27-33.
Trentman TL, Dodick DW, Zimmerman RS, Birch BD. Percutaneous occipital stimulator tip erosion: report of 2 cases.
Pain Physician 2008;11:253-256.
Trentman TL, Rosenfeld DM, Vargas BB, Schwedt TJ, Zimmerman RS, Dodick DW. Greater occipital nerve stimulation via the Bion microstimulator: implantation technique and stimulation parameters.
Clinical trial: NCT00205894. Pain Physician 2009;12:621-628.
Trentman TL, Slavin KV, Freeman JA, Zimmerman RS. Occipital nerve stimulator placement via a retromastoid to infraclavicular approach: a technical report.
Stereotact Funct Neurosurg 2010;88:121-125.
Vesper J, Bara G, Kinfe T, Schu S. Occipital nerve stimulation (ONS) for the treatment of chronic headache syndromes.
J Headache Pain 2013;14:P193.
Waisbrod G, Panhans C, Hansen D, Gerbershagen HU. Direct nerve stimulation for painful peripiheral neuropathies.
J Bone Joint Surg Am 1985;67-B:470-472.
Weiner RL, Alo KM, Feller C, et al. Nerve stimulation in the treatment of occipital neuralgia (p abs).
International Functional Electrical Stimulation Society Conference; 1998; Lucerne, Switzerland: Liste-88.
Weiner RL, Alo KM, Reed KL, Fuller ML. Subcutaneous neurostimulation for intractable C-2–mediated headaches
Annual AANS Meeting; 2001; Toronto, Canada: J Neurosurg: 938A.
Weiner RL, Reed KL. Peripheral neurostimulation for control of intractable occipital neuralgia.
Neuromodulation 1999;2:217-221.
Yakovlev AE, Resch BE. Treatment of chronic intractable atypical facial pain using peripheral subcutaneous field stimulation.
Neuromodulation 2010;13:137-140.
Zach KJ, Trentman TL, Zimmerman RS, Dodick D. Refractory headaches treated with bilateral occipital and temporal region stimulation.
Medical Devices: Evidence and Research 2014;7:55-59.